Thalassemia Unlinked to the @ - Globin Gene in an English Family
نویسنده
چکیده
An inherited hypochromic microcytic anemia transmitted in an autosomal manner has been observed in three generations of an English family. Affected members had the hallmarks of heterozygous @-thalassemia, ie, elevated levels of hemoglobin A, and imbalanced globin chain synthesis. However, despite extensive sequence analysis, no mutations could be found in or around the @-globin genes of either the propositus or two other affected members from
منابع مشابه
Beta-thalassemia unlinked to the beta-globin gene in an English family.
An inherited hypochromic microcytic anemia transmitted in an autosomal manner has been observed in three generations of an English family. Affected members had the hallmarks of heterozygous beta-thalassemia, ie, elevated levels of hemoglobin A2 and imbalanced globin chain synthesis. However, despite extensive sequence analysis, no mutations could be found in or around the beta-globin genes of e...
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